Reproductive Toxicology and Chemicals: a matter of timing?

Copenhagen 2-3 October 2003

a conference organized by 
the European Environment Agency and ReproSafe,
a research programme supported by the Swedish EPA


 
In reproductive toxicology “timing” has a certain meaning that creates true challenges for regulation of chemicals, environmental monitoring as well as risk assessment. One challenge is the so called "late effects." That is, the exposure may occur in utero or before puberty without any overt effect and then the adverse effects on reproductive functions are manifested in adulthood when the individual is supposed to be sexually functioning. Another is “critical or vulnerable windows”. That is, the reproductive system under development in the foetus and infant is much more sensitive to chemicals than the developed system in the adult. The latter challenge has for instance driven the U.S. EPA to apply an extra safety factor in assessing the risk of pesticides to children. An even broader initiative has recently started in the EU.

The conference invites experts as well as generalists from the organisations within the EU, the EU industry and NGOs, and in national governmental agencies and will focus on:

  • Presenting a scientific synopsis of the "timing" issues in reproductive toxicology for environmental chemicals, including recent research results from relevant EU & member states' research programme
     
  • Discussing implications of the “timing” issues for the management of chemicals, particularly exposure monitoring
     
  • Discussing EEAs role “in diffusion of information on the results of relevant environmental research in a form which can best assist policy development”, with particular regard to reproductive toxicology.
 
   
  For information please contact Mr. Ingvar Andersson at EEA (Phone: +45 33367115; e-mail: Ingvar.Andersson@eea.eu.int)
or Dr. Ulf Magnusson at ReproSafe (Phone: +46 18672324; e-mail: Ulf.Magnusson@og.slu.se).

The conference is free of charge, however the number of participants is limited.

The deadline for application is September 1st
register HERE (link to registration form).

 

 

 

 

 

 

PROGRAM

 

Thursday, 2 October 2003


12.00
Registration

Moderator: Ulf Magnusson, ReproSafe

 

13.00 Welcome

Gordon McInnes, Deputy Director EEA

Introduction to "Reproductive Toxicology and Timing"

Ulf Magnusson

Chemicals affecting reproduction - Overview of the classification in the EU and globally

Agneta Ohlsson, National Chemicals Inspectorate, Sweden

Late effects on reproduction in Fish

Susanne Jobling,
Brunel University, UK

Reproduction in birds - late effects and vulnerable windows

Björn Brunström, ReproSafe, Uppsala University, Sweden

Relevant animal models, vulnerable windows, and late effects in mammalian reproductive toxicology Rao Veeramachaneni, Colorado State University, USA

Low dose and late effects: Bisphenol A in mice

Paola Palanza, Parma University, Italy


19.00
Reception/Dinner



Friday, 3 October 2003


Moderator: Bo Jansson, EEA Scientific Committee

 

Start 8.30

Fertility, subfertility, infertility - comparisons between rodents and humans

 

Jorma Paranko, University of Turku, Finland

Late effects and vulnerable windows in human male reproduction

Niels Erik Skakkebaeck, Rigshospitalet, Denmark

Exposure monitoring of EDS; some implications of the "timing" issue

Monika Herrchen, Fraunhofer Insitute, Germany

How do current regulatory test methods for chemicals cope with late effects and vulnerable windows in reproductive toxicology?

Ulla Hass, Institute of Food Safety and Nutrition, Denmark

How do we manage these reproductive risks in the society?

Sven Ove Hansson, Royal Technical College, Sweden

12.15 Lunch

13.00 Reproductive toxicity testing - Industry's view Rick Becker, American Chemistry Council, USA
Reproductive toxicity testing :
An environmental NGO's perspective
Gwynne Lyons, WWF, UK

How can EEA communicate scientific results in this area?

Alister Scott, Sussex University, UK

Final Hearing/Discussion – all speakers

Lead by David Gee, EEA

15.00 Closing

David Stanners, EEA

 

 

Accommodation in Copenhagen
 

Invitees to meetings organised by the EEA can benefit from special rates granted by
some hotels situated in the area. The hotels listed here are all within 5-minute-walk
distance from the EEA.
Before actually making any reservation please note the following:

  1. The hotels list is provided for your convenience.

  2. Reservations are to be made directly by the invitee, in his/her own name

  3. In case of late arrival at the hotel (after 17.00h), it is up to the invitee to guarantee the reservation (by whatever means accepted by the hotel).

  4. Please note that once the booking has been confirmed, the hotel will invoice the first night in case of non-show unless cancellation has been made, preferable in writing, before 16.00h on arrival date.

  5. Invitees are requested to settle invoices directly with the hotel before checkout.

The EEA declines all responsibility for payment.
Unpaid invoices will be forwarded to the invitee in question.

 

2003 Rates
Hotels within five-minute walk from the EEA

Admiral Hotel  (****)
Toldbodgade 24-28
DK-1253 Copenhagen K
Tel.: +45-33 74 14 14
Fax: bookings: +45-33 74 14 16
Internet:
www.admiralhotel.dk

E-mail: admiral@admiral-hotel.dk

                                                Until 31.12.2003:
Single room:                                         895 DKK
Double room:                                      1130 DKK
Buffet breakfast:                         105 DKK/person
 

Customer nr.: 1312 (to be mentioned when booking)

Christian IV Hotel (***)
Dronningens Tværgade 45
DK-1302 Copenhagen K
Tel.: +45-33 32 10 44
Fax: +45-33 32 07 06
Internet:
www.arp-hansenhotelgroup.com

E-mail: hotelchristianiv@arp-hansen.dk
Central booking: +45-80 30 30 45
Central fax: +45-45 97 05 20

                 Until 31.03.03:       01.04.03-31.03.04:
Single standard:    925 DKK                   120 EUR
Single superior:   1010 DKK                   131 EUR
Double standard: 1180 DKK                   153 EUR
Double superior:  1265 DKK                   164 EUR
 

Buffet breakfast + VAT included.
5 EUR Environ. tax/room/night not included.

“Today’s special offer” to be checked on web site.

City Hotel (***)
Peder Skrams Gade 24
DK-1054 Copenhagen K
Tel.: +45-33 13 06 66
Fax: +45-33 13 06 67
Internet:
www.hotelcity.dk

E-mail: hotelcity@hotelcity.dk

                                                   Until 31.12.03:
Single room standard:                            796 DKK
Single room superior:                           1005 DKK
Double room standard:                         1050 DKK
Double room superior:                          1172 DKK
 

Breakfast + VAT + Environ. tax included

Clarion Hotel Neptun (****)
Sankt Annæ Plads 18-20
DK-1054 Copenhagen K
Tel.: +45-33 96 20 00
Fax: +45-33 96 20 66
Internet: www.choicehotels.dk

E-mail: info.neptun@clarion.choicehotels.dk
Free call – reservations: +45-8001 04 65

                                                   Until 31.12.03:
Single standard:                                  1295 DKK
Single superior:                                   1380 DKK
Double standard:                                 1515 DKK
Double superior:                                  1765 DKK
Suite:                                                 2070 DKK

Buffet breakfast + taxes included.